Genome Assembly and Scaffolding
Using the TELL-Seq™ Library Prep Kit you can sequence novel genomes. This works for small bacterial genomes, medium sized insect, plant, and fungi genomes and large animal and plant genomes. The TELL-Seq™ kit will turn an ordinary short-read 2nd generation DNA sequencer into a long-read 3rd generation DNA sequencer. Microbial Library kit is specifically designed for samples with less than 50Mb genome size to prepare TELL-Seq™ libraries with the least cost.
Samples containing disparate microbes are essential to gaining insight into our ecosystem as well as human disease. The TELL-Seq™ Library Prep Kit will allow you to sequence samples at a metagenomic scale; providing long-read like results with the ease of short-read sequencing. To see what is truly in a mixed microbial sample use the power of long-read with the simplicity of short-read sequencing.
Whole Genome Phasing and Targeted Phasing
Knowing which homologous chromosome has which sequence is essential to understanding a genome. Halotype Phasing is difficult with 2nd generation, short-read, DNA sequencing technology. Phasing provides haplotype information which is important for understanding complex traits and variant linkages. The TELL-Seq™ ibrary Prep Kit helps with this by linking short-reads to larger fragments and generate long-range information for both whole genome sequencing or targeted phasing applications.
Short-read DNA sequencers have trouble identifying large structural variants. These could be in the form of copy number variants, translocations, duplications, deletions, insertions, and inversions. The TELL-Seq™ Library Prep Kit links short-reads turning them into long-reads. The linked, long-read data that you get using the TELL-Seq™ kit will allow you to take a step back and see what you were missing.